Grape Seed, Resveratrol and Pomegranate Significantly Lower Blood Pressure

Adults aged 55 and older face a lifetime risk of developing elevated blood pressure greater than 90%, accounting for more than 40 million doctor visits each year and taxing an already overburdened healthcare system. Uncontrolled blood pressure slowly degrades the vascular system throughout the body and takes a particular toll on the kidneys, eyes and delicate arteries around the heart and in the brain.

Small increases in blood pressure place an individual at dramatically increased risk from heart attack, stroke, kidney failure and blindness. Researchers focusing on the antioxidant capacity of grape seed, resveratrol and pomegranate found that regular consumption of these foods can effectively reduce blood pressure without the need for dangerous prescription drugs.

Natural Fruit Polyphenols Lower Cellular Stress and Blood Pressure

Oxidative stress is a significant factor leading to accelerated damage from hypertension. Excess stress prompts changes to the hormone angiotensin that is known to impact blood pressure through an intricate mechanism of vessel and arterial constriction. Natural agents that can lower dangerous levels of cellular oxidative stress are considered paramount to lowering blood pressure in susceptible individuals.

ACE (angiotensin-converting enzyme)-inhibitors are among the most popular prescription medications prescribed to negate the effect of the angiotensin hormone, and create a life of misery for many due to the myriad of side effects inherent with this class of drug. Recent research shows that artificially lowering blood pressure with drugs has virtually no effect on cardiovascular disease risk, compared to lowering readings with natural fruit polyphenols, diet and physical activity.

Study Shows That Grape Seed Extract and Resveratrol Can Effectively Lower Blood Pressure

Writing in the journal Metabolism, nutritional scientists compared the effect of grape seed extract and resveratrol on subjects with metabolic syndrome. Three groups were divided to receive either grape seed extract (GSE) at a dose of 150 mg per day, GSE at 300 mg per day or a placebo. After 4 weeks, both GSE supplemented groups experienced systolic blood pressure drops of 5 to 7 percent. This change was considered significant as no other dietary or lifestyle interventions were followed. Researchers believe that GSE and grape-derived compounds including resveratrol can be used to prevent and treat hypertension based on the potent antioxidant load delivered by the fruit extracts.

Pomegranates effectively lower blower blood pressure in a manner similar to GSE and resveratrol as the juice and extracts contain powerful polyphenols that counteract oxidative stress. This magical fruit also is found to lower circulating levels of the angiotensin hormone that can help blood vessels to relax. The result of a study published in the journal Atherosclerosis demonstrated that consumption of pomegranate juice (50 ml per day for 2 weeks) lowered ACE activity by 36%, leading to a 5% drop in systolic blood pressure.

It should come as no surprise to those following a natural health lifestyle that the key to controlling blood pressure and reducing the risk factors that promote cardiovascular disease are not found in a prescription bottle. Fruits such as the pomegranate and formulated natural extracts from red grape skins and seeds deliver powerful health benefits without any of the associated side effects of synthesized pharmaceuticals.

Read more »

Posted in: Blood Pressure,Grape Seed,Pomegranate,Resveratrol

Pomegranate Fights Cancer and Lowers Heart Disease Risk

(Article first published as Pomegranate Lowers Cancer Risk and Boosts Heart Health on Technorati.)

Pomegranates are a gift from nature that provide powerful multi-modal health benefits. Extracts and the juice from this super fruit are shown to lower the damaging effects from systemic inflammation that are now associated with the development of many deadly diseases. 

Pomegranates have one of the highest antioxidant ORAC scores that help to neutralize the cellular and DNA damaging effects of free radicals that accelerate aging. Pomegranates are a tasty way to provide protection from the risk of developing many forms of cancer, cardiovascular and renal disease as well as stroke and dementia.

Pomegranate in the Fight against Cancer Proliferation

One of the hallmark signs of cancer progression is when cells lose their adhesive properties and break away to different parts of the body in a process known as metastasis. This mechanism of cellular transit provides for the deadly nature of many cancer lines, specifically prostate cancer. The result of research presented to the American Society for Cell Biology shows that pomegranate-treated tumor cells increased cell adhesion and decreased cell migration that can prevent the disease from spreading to different parts of the body.

The researchers conducting this study explain that their results would apply to most types of cancer. While the results of this study pertain specifically to prostate cancer proliferation, they can be applied to most cancer cell lines due to the migratory nature of this disease. The lead research author concludes “we can now modify cancer-inhibiting components in pomegranate juice to improve their function and make them more effective in preventing prostate cancer metastasis, leading to more effective therapies."

Antioxidant Nature of Pomegranate Modifies Blood Lipids, Lowers Blood Pressure

The active compound in pomegranate is called ellagitannin and is credited for the powerful antioxidant capacity claimed by this super fruit. Pomegranate has been shown to influence gene expression and suppress the pro-inflammatory cytokine, nuclear factor-kappaB (NF-kB). The fruit also activates an enzyme that is responsible for generating the artery-cleansing HDL cholesterol.

Information presented to the American Society of Nephrology reveals how pomegranate can inhibit the development of oxidized LDL cholesterol particles that become lodged in arterial vessel walls and cause arterial stiffening and increased blood pressure. Researchers found that extracts from the juice reduce the number of potentially fatal atherosclerotic lesions and protect the vascular system from damage, reducing the risk from a cardiovascular event.

Pomegranate is beneficial to human health because of its powerful antioxidant and anti-inflammatory properties. For optimal protection against heart disease and cancer, nutritional researchers advise drinking 8 ounces of the juice daily, combining the contents of an entire pomegranate into a smoothie or supplementing with 400 mg of concentrated extract. Health conscious individuals will certainly want to take advantage of this super fruit to dramatically lower risk from multiple disease processes.

Read more »

Posted in: Cancer,Heart Disease,Pomegranate